📚 Research & Publications

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Peer-reviewed research advancing the understanding of endometrial biology and reproductive health

Featured Publication
2023

Deciphering Key Genes of Proliferative and Secretory Phase Using Integrated Transcriptomics and Network Analysis

Authors

Payal GuptaShriya DubePayal PriyadarshiniShanvi SinghAnasuya Pravallika RVijay Lakshmi SrivastavaPriyanka NaradAbhishek Sengupta

Journal

Microbiology and Biotechnology Letters

Published

September 28, 2023

Received

April 26, 2023

Accepted

June 28, 2023

Abstract

This study focuses on endometrium receptivity, aiming to identify differentially expressed genes and associated pathways during the shift from the proliferative to the secretory phase. Researchers retrieved raw data from six GEO datasets, identified 705 differentially expressed genes (DEGs), and further validated 20 key genes in an additional dataset. These identified genes are considered major biomarkers for the transition between the proliferative and secretory phases.

Key Highlights

Analyzed 6 GEO datasets for comprehensive gene expression profiling
Identified 705 differentially expressed genes (DEGs)
Validated 20 key biomarker genes in an independent dataset
Revealed critical pathways for proliferative to secretory phase transition

Keywords

EndometriumProliferative PhaseTranscriptomics AnalysisNetwork AnalysisReproductive HealthBioinformatics
DOI:10.48022/mbl.2304.04008
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